kcl22 cells Search Results


90
JCRB Cell Bank cml cell lines kcl22
Cml Cell Lines Kcl22, supplied by JCRB Cell Bank, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Shanghai Industrial Co Ltd human chronic myelogenous leukemia kcl-22 cells
Human Chronic Myelogenous Leukemia Kcl 22 Cells, supplied by Shanghai Industrial Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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90
European Collection of Authenticated Cell Cultures kcl22
GI 50 values of tested compounds for <t> KCL22 </t> cells containing Bcr-Abl WT or mutated kinase domain in T315I (B8), E255K (F4), or Y253H (B10).
Kcl22, supplied by European Collection of Authenticated Cell Cultures, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kcl22+cells/pmc11125181-285-0-22?v=European+Collection+of+Authenticated+Cell+Cultures
Average 90 stars, based on 1 article reviews
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CEM Corporation gapdh kcl22 probe
GI 50 values of tested compounds for <t> KCL22 </t> cells containing Bcr-Abl WT or mutated kinase domain in T315I (B8), E255K (F4), or Y253H (B10).
Gapdh Kcl22 Probe, supplied by CEM Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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KinaSense LLC cml cell lines kcl22 and kcl22-ir
Calculated LogP and anti-proliferation activities of alkynyl analogs
Cml Cell Lines Kcl22 And Kcl22 Ir, supplied by KinaSense LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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National Centre for Cell Science human myeloid cell line kcl-22
Calculated LogP and anti-proliferation activities of alkynyl analogs
Human Myeloid Cell Line Kcl 22, supplied by National Centre for Cell Science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


GI 50 values of tested compounds for  KCL22  cells containing Bcr-Abl WT or mutated kinase domain in T315I (B8), E255K (F4), or Y253H (B10).

Journal: Pharmaceutics

Article Title: New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs

doi: 10.3390/pharmaceutics16050649

Figure Lengend Snippet: GI 50 values of tested compounds for KCL22 cells containing Bcr-Abl WT or mutated kinase domain in T315I (B8), E255K (F4), or Y253H (B10).

Article Snippet: Human cell lines KCL22 and BV173 were obtained from the German Collection of Microorganisms and Cell Cultures, K562 and HEK-293T from the European Collection of Authenticated Cell Cultures.

Techniques:

Calculated LogP and anti-proliferation activities of alkynyl analogs

Journal: ChemMedChem

Article Title: Alkynylnicotinamide-based compounds as ABL1 inhibitors with potent activities against drug-resistant CML harboring ABL1(T315I) mutant kinase.

doi: 10.1002/cmdc.201700829

Figure Lengend Snippet: Calculated LogP and anti-proliferation activities of alkynyl analogs

Article Snippet: Evaluation of compounds activity against ABL1 and ABL1(T315I) inside CML cell lines KCL22 and KCL22-IR (by KinaSense, West Lafayette, IN, USA).

Techniques:

Inhibition of cellular ABL1 activity by imatinib, ponatinib and HSN compounds

Journal: ChemMedChem

Article Title: Alkynylnicotinamide-based compounds as ABL1 inhibitors with potent activities against drug-resistant CML harboring ABL1(T315I) mutant kinase.

doi: 10.1002/cmdc.201700829

Figure Lengend Snippet: Inhibition of cellular ABL1 activity by imatinib, ponatinib and HSN compounds

Article Snippet: Evaluation of compounds activity against ABL1 and ABL1(T315I) inside CML cell lines KCL22 and KCL22-IR (by KinaSense, West Lafayette, IN, USA).

Techniques: Inhibition, Activity Assay